daughters. is it a good idea? plus, one of the most popular bands of all time, journey, live on the central stage, after your local news.wsy . it's a cloud of depression. and although you've been on an antidepressant for at least six weeks, you're frustrated that your depressive symptoms are still with you. seroquel xr, when added to an antidepressant, is approved for the treatment of major depressive disorder. for many, taking seroquel xr with an antidepressant was proven more effective for treating unresolved symptoms of depression than an antidepressant alone. call your doctor if you have unusual changes in mood, behavior, or thoughts of suicide. antidepressants can increase these in children, teens, and young adults. elderly dementia patients taking seroquel xr have an increased risk of death. call your doctor if you have fever, stiff muscles, and confusion, as these may be signs of a life-threatening reaction or if you have uncontrollable muscle movements, as these could become permanent.